7/5/2023 0 Comments Vitamins for memoryThe mechanism of action is in its ability for free radical scavenging and as an antioxidant. The active compounds of GBE are primarily flavonol glycosides (24%) and terpene compounds, such as ginkgolides and bilobalide (6%), with smaller amounts of proanthocyanidins (4). Ginkgo biloba extract (GBE) is used as a single ingredient and also typically in combo products for brain health and neurotransmitter support, which is important for cognition. A recent randomized clinical trial indicated that a 3-year folic acid supplementation can help to reduce the age-related decline in cognitive function. Taking folate as an additional supplement or in a B complex may help prevent cognitive decline and dementia as we age. Adequate levels of folate are essential for brain function, and a deficiency can lead to neurological disorders, such as depression and cognitive impairment. Folate deficiency, commonly caused by low dietary intake, has been associated with physiological abnormalities that may occur during development and adulthood. (2) Taking a B complex along the B12 or a methylated form, if needed, will help increase the absorption.Īfter the consumption of folate or folic acid, found in various foods, including spinach and oranges, the liver generates several forms of folate after the intestine has absorbed vitamin B. There is also a continuous inverse relationship between serum B12 and a variety of undesirable outcomes, including neural tube defects, stroke, and dementia. The goal would be to get a patient’s B12 level between 900-1200 pg/mL and a homocysteine level under 7 mcmol/L. Typically, an elevation over 12 mcmol/L is an inflammatory marker for the heart, and any value over 7 mcmol/L can indicate the susceptibility to neurodegeneration. Methionine is essential, and any interference in the synthase reaction can lead to the elevation of homocysteine. One of its functions is as a cofactor for the enzymes methionine and methylmalonylCoA mutase. Vitamin B12, which we commonly see in practice in much lower than optimal amounts, may also play a very important role. A rare occurrence, scary dreams are also possible, so should that occur, a reduction in dosage or complete elimination may be necessary. One side effect to note is the increase in strange and colorful dreams. If the problem is lack of sleep or the inability to fall asleep, then taking it at bedtime will provide the additional benefit of better sleep. (1) If stress level is high, taking PS during the day can serve a dual purpose. (1) It has been demonstrated to support human cognitive functions, including the formation of short-term memory, the consolidation of long-term memory, and the ability to learn and recall information, the ability to focus attention and concentrate, the ability to reason and solve problems, language skills, and the ability to communicate. Up to 800mg/d can be absorbed and crosses the blood-brain barrier, all while safely slowing, halting, or reversing biochemical alterations and structural deterioration in nerve cells. Phosphatidylserine (PS), commonly used in adrenal dysfunction to lower cortisol levels, is necessary for healthy nerve cell membranes and myelin. There is some evidence, however, to support a handful of nutrients for brain health and also may help slow the decline of our memory. Many made claims that could not be substantiated. Published in the Journal of Alternative and Complementary Medicine in April 2020 was an interesting review titled: “A Public Health Issue: Dietary Supplements Promoted for Brain Health and Cognitive Performance.” There were 650 products evaluated that targeted brain health. While some of us and our patients are maybe years away from that number, others of us have crossed into the probability of that statistic, and it is a growing concern that has the supplement industry targeting those with symptoms. It is a popular area of study, and, when I take a look into the statistics, the average reported number is that 1 in 8 people suffer from some sort of memory deficit in the United States, with a large portion being those of us who are over 65 years in age. 21, 2022.Lately, it seems as though every time I open up my News app on my phone, there is an article about memory loss, dementia, or Alzheimer’s. National Institute of Neurological Disorders and Stroke. Centers for Disease Control and Prevention. Recommended amount of sleep for a healthy adult: A joint consensus statement of the American Academy of Sleep Medicine and Sleep Research Society. Physical Activity Guidelines for Americans.Dementia prevention, intervention, and care. Risk factors for cognitive decline and dementia. Understanding memory loss: What to do when you have trouble remembering.
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